Sure there is. If we [who determine the definition of "general Welfare"] decide that the poster-child for that phrase ie: univeral healthcare is what we want for ourselves, we have the power in Article I, Section 8, line 1 to enact legislation to provide universal healthcare as long as the distribution of tax collection for that service is collected equally among the States.
Here it is again for quick reference:
The words "general Welfare' are not subject to a hard and fixed predetermined interpretation. They are up to us to interpret via our elected officials and their decision making. If there ever was a case besides protection of civilian life and limb in the military to fund a public entity also for protection of life and limb, it would be universal care.
I often wonder why the clone-army doesn't blog about eliminating medicaid, and the ER coverage we all now pay for anyway? They are equally offensive to their platform, so why the silence? Hmmm? Could it be that if the clone-army tried to reverse Medicaid they would run up against a screaming majority with torches in hand? All we want is to streamline what already exists, to save taxpayers money. Y'all are supposedly against taxpayer waste.
Conclusion: Y'all are talking out of both sides of your collective mouth. So which is it? Do you want to save the taxpayer money or do you want to cost them more via the current Bill as it panders to MedMob, subsidizing them getting 30 million new customers at elevated premiums we will pick up the tab for or are you for eliminating that gross expenditure, streamlining it and cutting clerical and advertising costs [a huge segment of overhead] out of our obligations to provide the same, or better level of care?
Personally I'd rather put the money we'll save not paying jacked premium subsidies for the uninsured to private sheisters and instead put that money into providing better care for the care already mandated to be provided by the taxpayers via the de facto [and most wasteful] universal care system now called "ER visits and Medicaid". We have a right to save ourselves money. Yes, we do..
Article I Section 8 also states "but all Duties, Imposts and Excises shall be uniform throughout the United States."
Therefore, excluding some states (like Nebraska) seems like it would be unconstitutional going by the language in the article you are citing.
Putting all of that aside, if people can successfully make the 10th amendment argument, it will be a toss up where the courts will come down in my opinion... especially if state governments pass legislation barring the implementation of the legislation.