It has nothing to do with the drones themselves, no. It has to do with who is controlling the drones.
We are not at war with Yemen, nor are we at war with Pakistan.
And no one is using drones in the US for more than surveillance yet.
And when and if it happens the first time, I'd not like to see only the people who support the party opposite that of the president protest. I'd like to see the country protest.
But, more than likely, one more escalation in the "war on terror" won't bring much of an outcry except that motivated by partisanship.
It is established policy via the "Bush Doctrine" that we make no distinction between terrorists and foreign governments that harbor terrorism. Therefore, it has been established policy for basically a decade that we will target identified terrorists in places like Yemen if the local governments will not work with us to capture them.